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Vitamins

Vitamin B6

Vitamin B6 is considered essential for amino acid metabolism during exercise, which may directly support muscle protein synthesis and recovery. Active individuals may have increased requirements. Consult a sports medicine professional for optimal assessment.

Doctor's Assessment Included

Reference Ranges

See the value that applies to you:

Choose male or female — this range differs by sex.

Enter your age — this range changes with age.

This range also depends on context such as cycle phase or sample material; the highlighted rows apply to your group.

Male Your group
nmol/l
Low 20 Normal 125 High
Female Your group
nmol/l
Low 20 Normal 125 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

Check your own value

What It Measures

This test measures vitamin B6 (pyridoxal phosphate) levels in your blood, expressed in nmol/l. It may help assess whether your body has adequate B6 for amino acid metabolism and neurotransmitter production. Your healthcare provider can provide personalised interpretation.

Why It Matters

For active individuals, vitamin B6 may be critical for protein metabolism, glycogen utilisation, and neurotransmitter production that affects focus and motivation. Suboptimal levels have been associated with impaired recovery and decreased performance. Discuss results with a sports medicine professional.

When to Test

Testing may be considered when experiencing mood changes, peripheral neuropathy, weakened immunity, or anaemia symptoms. Healthcare providers may also recommend testing for individuals taking certain medications, those with kidney conditions, or people with limited dietary variety.

Symptoms

Low Levels

Some people with low vitamin B6 may experience irritability, depression, confusion, mouth sores, or a weakened immune response. Peripheral neuropathy with numbness and tingling has also been reported. A healthcare provider can help identify the cause of these symptoms.

High Levels

Elevated vitamin B6 levels, typically from excessive supplementation, may sometimes be associated with nerve damage causing numbness or difficulty with coordination. Some people may experience skin sensitivity. Consult your healthcare provider if your levels appear elevated.

Recommendations

Male

If Low

Low vitamin B6 may cause neurological symptoms. Consider supplementation.

If High

High vitamin B6 may cause neuropathy at prolonged high doses. Reduce supplementation.

Female

If Low

Low vitamin B6 may worsen PMS symptoms. Consider supplementation (50–100 mg daily).

If High

High vitamin B6 may cause neuropathy. Reduce supplementation.

Lifestyle Tips

Foods considered rich in vitamin B6 include poultry, fish, potatoes, chickpeas, bananas, and fortified cereals. A varied diet typically provides adequate amounts. Some people may benefit from discussing supplementation with their healthcare provider, especially if on restricted diets.

Frequently Asked Questions

How does vitamin B6 affect mood and mental health?
Vitamin B6 is believed to be involved in producing neurotransmitters such as serotonin and dopamine, which may influence mood regulation. Low levels have been associated with mood changes in some studies. Discuss any concerns about mood with your healthcare provider.
Can you take too much vitamin B6?
Excessive vitamin B6 intake from supplements over prolonged periods may potentially cause nerve damage in some individuals. This is generally not a concern with food sources alone. Always follow your healthcare provider's recommendations regarding supplementation dosages.
Does vitamin B6 interact with medications?
Certain medications, including some used for epilepsy, tuberculosis, and autoimmune conditions, may affect vitamin B6 levels. If you are taking medications, consult your healthcare provider about whether B6 monitoring or supplementation may be appropriate for you.

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