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Doctor's Assessment Included

Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.

Hormones

Estradiol (E2)

Estradiol (E2) plays a role in bone health, recovery, and joint protection for active individuals. Balanced estrogen levels may support training adaptation and injury prevention. Your healthcare provider can help determine whether your levels are optimal for your performance goals.

Reference Ranges

Male
pmol/l
Low 41 Normal 159 High
Female
pmol/l
Low 46 Normal 607 High

Reference ranges may vary between laboratories. When you order a test, a BIG-registered doctor assesses your personal results in context. For treatment decisions, discuss your results with your GP.

What It Measures

This test measures the concentration of estradiol (E2) in your blood. Estradiol is produced primarily by the ovaries in women and in smaller amounts by the testes and adrenal glands in men. Your healthcare provider may use this result alongside other hormone levels.

Why It Matters

For active individuals, estradiol supports bone mineral density, reduces stress fracture risk, and may influence recovery between training sessions. Imbalanced levels could suggest overtraining or relative energy deficiency. Consult your healthcare provider to evaluate your hormonal profile.

When to Test

Your healthcare provider may recommend testing estradiol when investigating irregular menstrual cycles, fertility concerns, menopausal symptoms, or unexplained mood changes. For men, testing could be suggested when evaluating gynecomastia or other hormonal concerns. Consult your provider for personalised timing advice.

Symptoms

Low Levels

Some people may experience hot flashes, night sweats, mood changes, vaginal dryness, or decreased bone density when estradiol levels are low. Fatigue and difficulty concentrating could also suggest reduced estradiol. A healthcare provider can help determine the cause and recommend appropriate support.

High Levels

Elevated estradiol levels may be associated with bloating, breast tenderness, mood swings, or irregular periods in women. In men, high levels could suggest gynaecomastia or reduced libido. Your healthcare provider can evaluate whether further investigation is needed based on your symptoms.

Recommendations

Male

If Low

Low estradiol in men may indicate hypogonadism or pituitary dysfunction. Consider consulting an endocrinologist for evaluation and possible testosterone replacement therapy.

If High

Elevated estradiol in men may indicate obesity, liver disease, or use of certain medications. Consider weight management, liver function tests, and medication review.

Female

If Low

Low estradiol may indicate menopause, ovarian dysfunction, or eating disorders. Consider hormone replacement therapy if menopausal, or evaluation for underlying conditions.

If High

High estradiol levels may indicate ovarian tumors, pregnancy, or hormone therapy. Consult with a gynecologist or endocrinologist for proper evaluation.

Lifestyle Tips

Maintaining a healthy weight, regular physical activity, and a balanced diet rich in fibre and cruciferous vegetables may support healthy estrogen metabolism. Limiting alcohol intake and managing stress could also contribute to hormonal balance. Always discuss lifestyle changes with your healthcare provider.

Frequently Asked Questions

What is estradiol?
Estradiol is the strongest form of estrogen, important for reproductive and bone health.
When should I test estradiol?
Your provider may suggest testing during fertility evaluation or when experiencing hormonal symptoms.
Can lifestyle affect estradiol levels?
Diet, exercise, and body weight may influence estradiol. Discuss changes with your healthcare provider.

Test Products

This marker is included in the following test panels.

Health Checkups

InsideTracker

A 36-biomarker performance and longevity panel inspired by InsideTracker Ultimate — covering heart, hormones, metabolism, inflammation, recovery and iron status.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol GGT (Gamma-Glutamyl Transferase) Cortisol DHEA-S Estradiol (E2) Free Testosterone Total Testosterone Folate (Folic Acid) Vitamin B12 Calcium Ferritin Iron (Serum) Magnesium Magnesium (Intracellular) Potassium Progesterone Sodium Transferrin CRP (C-Reactive Protein) Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Total Cholesterol Albumin AST (Aspartate Aminotransferase) Vitamin D (25-OH) Insulin (Fasting) Leukocyte Differential Creatine Kinase (CK) Transferrin Saturation Triglycerides Complete Blood Count (CBC)
€399,-
Hormones & TRT

TRT Monitoring

Monitoring panel for testosterone replacement therapy: hormones, liver, lipids, PSA, and blood count.

PSA (Prostate-Specific Antigen) Prolactin ALT (Alanine Aminotransferase) Triglycerides ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) GGT (Gamma-Glutamyl Transferase) LDL Cholesterol SHBG (Sex Hormone Binding Globulin) Estradiol (E2) Free Testosterone Total Testosterone HDL Cholesterol Albumin Complete Blood Count (CBC)
€250,-

Whoop

A 44-biomarker comprehensive health panel inspired by WHOOP Advanced Labs — a deep look at metabolism, cardiovascular risk, hormones, liver, kidney and inflammation.

SHBG (Sex Hormone Binding Globulin) TSH (Thyroid Stimulating Hormone) ALT (Alanine Aminotransferase) LDL Cholesterol Cortisol DHEA-S Estradiol (E2) Free Testosterone FSH (Follicle Stimulating Hormone) LH (Luteinizing Hormone) Total Testosterone Bicarbonate Calcium Chloride Ferritin Iron (Serum) Magnesium Potassium Sodium Transferrin CRP (C-Reactive Protein) Homocysteine Glucose (Fasting) HbA1c (Glycated Hemoglobin) ApoB (Apolipoprotein B) HDL Cholesterol Omega-3 Index Total Cholesterol Albumin HOMA-IR ALP (Alkaline Phosphatase) AST (Aspartate Aminotransferase) Bilirubin (Total) Total Protein Urea (BUN) Creatinine Vitamin D (25-OH) eGFR (Estimated Glomerular Filtration Rate) Insulin (Fasting) Leukocyte Differential Transferrin Saturation Lipoprotein(a) Triglycerides Complete Blood Count (CBC)
€499,-